Parametrization of Catalytic Organic Reactions with Convex Hammett Plots

Quantification is essential to fairly compare between synthetic reactions in chemistry. Here we propose two new parameters called “adapted sensitivity constant” (ρadap) and “substrate electronics adaptability” (SEA), easily obtainable from Hammett plots, assess the ability of a (catalytic) reaction transform substrates with opposing electronics. These allow one list reactions, catalyzed or not, as function substrate scope.